Novo Nordisk A/S - share repurchase programme

Bagsværd, Denmark, 19 October 2026 – On 6 May 2026, Novo Nordisk initiated a share repurchase programme in accordance with Article 5 of Regulation No 596/2014 of the European Parliament and Council of 16 April 2014 (MAR) and the Commission Delegated Regulation (EU) 2016/1052 of 8 March 2016 (the "Safe Harbour Rules"). This programme is part of the overall share repurchase programme of up to DKK 15 billion to be executed during a 12-month period beginning 4 February 2026. Under the programme initiated 6 May 2026, Novo Nordisk will repurchase B shares for an amount up to DKK 11,200,000,010.45 in the period from 6 May 2026 to 1 February 2027. Since the announcement 12 October, the following transactions have been made: ──────────────────────────┬───────────────┬──────────────────┬────────────────── │Number of │Average │Transaction │B shares │purchase price │value, DKK ──────────────────────────┼───────────────┼──────────────────┼────────────────── Accumulated, last │23,090,000 │ │6,758,876,433 announcement │ │ │ ──────────────────────────┼───────────────┼──────────────────┼────────────────── 12 October 2026 │250,000 │257.41 │64,351,856 ──────────────────────────┼───────────────┼──────────────────┼────────────────── 13 October 2026 │245,000 │258.17 │63,251,159 ──────────────────────────┼───────────────┼──────────────────┼────────────────── 14 October 2026 │245,000 │254.86 │62,441,019 ──────────────────────────┼───────────────┼──────────────────┼────────────────── 15 October 2026 │245,000 │259.36 │63,543,405 ──────────────────────────┼───────────────┼──────────────────┼────────────────── 16 October 2026 │240,000 │260.67 │62,560,442 ──────────────────────────┼───────────────┼──────────────────┼────────────────── Accumulated under the │24,315,000 │ │7,075,024,314 programme │ │ │ ──────────────────────────┴───────────────┴──────────────────┴────────────────── The details for each transaction made under the share repurchase programme are published on novonordisk.com. With the transactions stated above, Novo Nordisk owns a total of 53,114,876 B shares of DKK 0.10 as treasury shares, corresponding to 1.2% of the share capital. The total amount of A and B shares in the company is 4,465,000,000 including treasury shares. Novo Nordisk expects to repurchase B shares for an amount up to DKK 15 billion during a 12-month period beginning 4 February 2026. As of 16 October 2026, Novo Nordisk has since 4 February 2026 repurchased a total 39,074,179 B shares at an average share price of DKK 278.32 per B share equal to a transaction value of DKK 10,875,024,304. Novo is the global healthcare company that believes lasting health starts now. For over a century, we’ve combined leading scientific expertise with a deep understanding of people’s lives. We develop treatments and support that help millions of people make progress they can see, feel and sustain now and in the future. Every day, over 67,000 employees around the world advance our purpose to drive change for lasting health. Through our partnerships, programmes and investments, we’re working to prevent disease, expand access to treatments and reduce our environmental impact to help even more people live healthier lives. Novo Nordisk's B shares are listed on Nasdaq Copenhagen (Novo-B). Its ADRs are listed on the New York Stock Exchange (NVO). For more information, visit novonordisk.com and follow us on Instagram, LinkedIn, TikTok, Facebook, X and YouTube. Contacts for further information ────────────────────────────────────────┬─────────────────────────────────────── Novo Nordisk Media: │ ────────────────────────────────────────┼─────────────────────────────────────── Ambre James-Brown │Liz Skrbkova (US) +45 3079 9289 │+1 609 917 0632 globalmedia@novonordisk.com │USMediaRelations@novonordisk.com ────────────────────────────────────────┼─────────────────────────────────────── Novo Nordisk Investors: │ ────────────────────────────────────────┼─────────────────────────────────────── Michael Novod │Sina Meyer +45 3075 6050 │+45 3079 6656 nvno@novonordisk.com │azey@novonordisk.com ────────────────────────────────────────┼─────────────────────────────────────── Christoffer Togo Solgaard-Tullin │Max Ung +45 3079 1471 │+45 3077 6414 cftu@novonordisk.com │mxun@novonordisk.com ────────────────────────────────────────┼─────────────────────────────────────── Ida Schaap Melvold │Mads Berner Bruun +45 3077 5649 │+45 3075 2936 idmg@novonordisk.com │mbbz@novonordisk.com ────────────────────────────────────────┼─────────────────────────────────────── Frederik Taylor Pitter (US) │Alex Bruce (US) +1 609 613 0568 │+1 640 230 0276 fptr@novonordisk.com │axeu@novonordisk.com ────────────────────────────────────────┴─────────────────────────────────────── Company announcement No 62 / 2026 Attachments 20261019.Safe Harbour 20261019_Safe harbour transaction details [1]: https://www.globenewswire.com/Tracker?data=zm5DDU4vlyMeET8j1Y2fW6-XS8n4lqNE FQIUfqgIK6kamC3aJ1xA5EVGwNlFB1_LdgLn2Yk-f6L6zC4VS-Uny3DXZcnsl2apEO2_Ey-Xi77Ujb-y skMBX5yoATc1cmncc-9qN1ML_2gcrsGa0DqE_Y45G00R8h13yIXpADgqLWc= [2]: https://www.globenewswire.com/Tracker?data=zm5DDU4vlyMeET8j1Y2fW-LNrpdD8SDE HvBhkgmixkAuUohlk6W7DeAhwdJxkyOz9R3eJtQ6oRdynb9CIWn_ttL-LLRe_p0UPs8tZ_MlLKg= [3]: https://www.globenewswire.com/Tracker?data=rCiJYNQWT_0pxOQk-TLH87XBIXbw0vJD Y4P3aTjYBxjFZqFQouw5xLmFraoQ_H_RsTl6W8ksQTkzsmAhFfs3JdyDQK6UfqaGUsu3HHG3fvg= [4]: https://www.globenewswire.com/Tracker?data=88V82CwPE5Zta5E_4wOQlBu9-yOzFUE9 EFtch44Rod9uQxgLwA8dF55zLBj7IIuUQCGaCV6HqpUIXRUii9WNEvRuggZn8acr6VpN1-GesEhhhi_y cG53CE7Xw8Xzwp8T [5]: https://www.globenewswire.com/Tracker?data=LjSSGtDGdLLNswwfqQ0gUZgNy2LAlBjt 1ih2Z_zqaauPZHKNl_usS7BT2K2Eh5yLYG1kOW0VxNWphTWtFEVpYxzNcH3m8w33jteyesy9kXQ= [6]: https://www.globenewswire.com/Tracker?data=cYj4AO31-0Rpx--6nL12g7JHMbNPlu9J o9HRvqx7g4F57-Y_0iPhVFEAGGb1S4nw082TdOJdsoizVy_S_CkTCWHWSKT3aFbZMWx7sO05PGs= [7]: https://www.globenewswire.com/Tracker?data=Fcnjb7TZzc1xaIv4vRnrUhaVcdtP0v_D 0iJ6v5shI9pD3hT5Qrt2VAnOlrl1hFtx3p9O0kKPR0HwA5C6oDXu0g== [8]: https://www.globenewswire.com/Tracker?data=9fCT1uTbpGLlhkhJCSthpyuPgrhB08ue -h_0nq-C5P82A59LcDsu70jazPh1aaooacGNe3gJUU3ulEpp3--aUk08ZshvUgO-ATnFrsnh7is= [9]: mailto:globalmedia@novonordisk.com, [10]: mailto:USMediaRelations@novonordisk.com [11]: mailto:nvno@novonordisk.com [12]: mailto:azey@novonordisk.com [13]: mailto:cftu@novonordisk.com [14]: mailto:idmg@novonordisk.com [15]: mailto:idmg@novonordisk.com [16]: mailto:mbbz@novonordisk.com [17]: mailto:fptr@novonordisk.com [18]: mailto:axeu@novonordisk.com [19]: https://ml-eu.globenewswire.com/Resource/Download/92f8f6f8-8455-45d6-ae0d- f926506bcd7b [20]: https://ml-eu.globenewswire.com/Resource/Download/48387a38-c6a0-4af0-b135- 87d3be1fd05f